刘涛
刘涛 研究生导师
职称：研究员 学位：博士
学院: 针灸康复临床医学院（华南针灸研究中心）
E-mail: lt045021@gzucm.edu.cn
办公电话：15052648515
办公室：广州大学城广州中医药大学针灸楼320
个人获得荣誉：广州中医药大学“杏林青年学者”
教育、工作经历
(1) 2005/09-2009/06，西南交通大学，生命科学与工程学院，学士
(2) 2009-09至2014-06，西南交通大学，材料科学与工程学院，博士
(3) 2014-07至2019-09，淮阴工学院，江苏省介入医疗器械研究重点实验室，讲师
(4) 2016-12至2018-12，哈佛大学医学院附属斯波尔丁康复医院，博士后
(5) 2019-09至今，广州中医药大学，针灸康复临床医学院，研究员
研究方向
(1) 从事微针经皮给药系统研究，结合材料学、生物医学和药学方法，构建具有微纳米结构特征的可降解微针阵列，负载具有特定功能活性的药物组方或单体化合物，通过经穴透皮给药的方式实现对病灶位点的局部有效治疗。
(2) 从事纳米药物传递系统开发。采用天然生物分子或药物分子构建纳米载体，用于药物靶向输运、药物洗脱材料及智能响应型药物系统的构建，提高载药效率，改善药物稳定性和安全性。
科研及教学课题
1. 国家自然科学基金面上项目，32071329，心血管材料表面载miRNAs纳米涂层的构建及其精准调控血管内膜原位修复的机制研究，2021/01-2024/12，59万元，在研，主持。
2. 国家自然科学基金青年项目，31500778，载SDF-1α/Cu(II)的抗凝纳米颗粒涂层对心血管材料表面原位内皮修复的影响及机制研究，2016/01-2018/12，21万元，已结题，主持。
3. 广东省自然科学基金面上项目，2021A1515011274，载miRNAs纳米涂层的构建及其精准调控血管内膜原位修复的机制研究，2021/01-2023/12，10万元，在研，主持。
承担的课程
承担《材料学》课程的本科教学。
代表性论文论著
(1) Jianying Tan, Li Li, Huanran Wang, Lai Wei, Xiali Gao, Zheng Zeng, Sainan Liu, Yonghong Fan, Tao Liu*, Junying Chen*. Biofunctionalized fibrin gel co-embedded with BMSCs and VEGF for accelerating skin injury repair. Mater Sci Eng C Mater Biol Appl, 2021, 121:111749.
(2) Tao Gong, Qinghua Hu, Xiaobo Nie, Tao Liu*, Hongqing Wang*. Periodic Dynamic Regulation of MSCs Differentiation on Redox-Sensitive Elastic Switched Substrates. ACS Applied Bio Materials, 2020, 3(6):3612-3620.
(3) Xin Wang, Zhaoxiang Meng , Yingzhu Chen, Yuping Li, Hongyu Zhou, Man Yang, Tingting Zhao, Yulai Gong, Yi Wu*, Tao Liu*. Enriched environment enhances histone acetylation of NMDA receptor in the hippocampus and improves cognitive dysfunction in aged mice. Neural Regeneration Research, 2020, 15(12):2327-2334.
(4) Xin Wang#, Tao Liu#, Haixin Song, Shaoyang Cui, Gang Liu, Andrea Christforou, Patrick Flaherty, Xun Luo, Lisa J. Wood, Qing Mei Wang*. Targeted Metabolomic Profiling Reveals Association Between Altered Amino Acids and Poor Functional Recovery After Stroke. Frontiers in Neurology, 2020, 10:1425.
(5) Shihui Liu, Youdong Hu, Rongrong Tao, Qingwei Huo, Lin Wang, Chunzhi Tang, Changjiang Pan, Tao Gong, Nenggui Xu*, Tao Liu*. Immobilization of fibronectin-loaded polyelectrolyte nanoparticles on cardiovascular material surface to improve the biocompatibility. BioMed Research International, 2019, 9: 1-9.
(6) Wenshu Luo#, Tao Liu#, Shanshan Li, Hongmei Wen, Fenghua Zhou, Ross Zafonte, Xun Luo, Minghzu Xu, Randie Black-Schaffer, Lisa J. Wood, Yulong Wang*, Qing Mei Wang*. The Serum BDNF Level Offers Minimum Predictive Value for Motor Function Recovery After Stroke. Translational Stroke Research, 2019, 10, 342-351.
(7) Tao Liu, Xin Wang, Xiaohan Tang, Tao Gong, Wei Ye, Changjiang Pan, Hongyan Ding, Xun Luo, Xia Li, Qing Mei Wang. Surface Modification with ECM-Inspired SDF-1α/Laminin-Loaded Nanocoating for Vascular Wound Healing. ACS Appl Mater Inter, 2017, 9 (36), 30373–30386.
(8) Tao Liu*, Youdong Hu, Jianying Tan, Shihui Liu, Junying Chen, Xin Guo, Changjiang Pan, Xia Li*. Surface biomimetic modification with laminin-loaded heparin/poly-l-lysine nanoparticles for improving the biocompatibility. Materials Science and Engineering: C, 2017, 17, 929-936.
(9) Tao Liu*, Junying Chen. Nanotechnology in Coronary Artery Stent Coating. Biomedical Nanomaterials (eds Y. Zhao and Y. Shen). Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. 2016, 437-463.
(10) Tao Liu, Yang Liu, Yuan Chen, Shihui Liu, Manfred Maitz, Xue Wang, Kun Zhang, Jian Wang, Yuan Wang, Junying Chen*, Nan Huang. Immobilization of heparin/poly-l-lysine nanoparticles on dopamine coated surface to create a heparin density gradient for selective direction of platelet and vascular cell behavior. Acta biomaterialia, 10(5), 2014, 1940-1954.
